Tricarboxylic acids and derivatives
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, 3 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, is a high-purity reagent used in laboratory applications, including buffer preparation and biochemical research. This 3 kg package ensures that researchers and laboratories have access to a reliable source of high-quality trisodium citrate for a variety of chemical and biological processes. The ACS-grade purity guarantees that the reagent meets the rigorous standards required for accurate and reproducible results. Sodium citrate is commonly used in the preparation of solutions for protein and enzyme assays, as well as for maintaining pH stability in a variety of applications including chromatography, electrophoresis, and molecular biology.
eMolecules 59085-15-3 | 4-(2-Carboxyethyl)-4-nitro heptanedioic acid | MFCD00077684 | 25g
Combi-Blocks | 4-(2-Carboxyethyl)-4-nitro heptanedioic acid | 25g | 495744957 | QK-4724 | 95.000 | 59085-15-3 | MFCD00077684 | 277.229 | C10H15NO8
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Medchemexpress LLC Dicresulene diammoni 50mg | 50MG
Dicresulene diammonium is an impurity of Policresulen an organic acid with hemostatic antimicrobial and antiviral activities[1 [2
Medchemexpress LLC PEG3-O-CH2COOH (PROTAC Linker 8) | 51951-05-4 | ≥95.0% | 100 MG
PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker designed for use in the synthesis of SNIPERs. These SNIPERs recruit inhibitor of apoptosis protein (IAP) ubiquitin ligases to specifically degrade targeted proteins, offering a valuable tool for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of SNIPERs
- Recruits inhibitor of apoptosis protein (IAP) ubiquitin ligases
- Designed to specifically degrade targeted proteins
- For research use only
Selleck Chemical LLC Sodium citrate dihydrate
Sodium citrate dehydrate (Trisodium citrate dihydrate Citric acid trisodium salt dihydrate) is the preferred anticoagulant
Medchemexpress LLC Dimal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 25 MG
diMal-O-CH2COOH is a cleavable ADC linker. It is categorized under Antibody-drug Conjugate/ADC Related and ADC Linker, making it suitable for applications in cancer and cancer targeted therapy.
- Cleavable ADC linker
- White to off-white solid appearance
- Molecular weight: 308.24
- Suitable for antibody-drug conjugate related applications
Medchemexpress LLC MRTX9768 | 2629314-68-5 | 99.48% | 424.43 | 50 MG
MRTX9768 is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor. It inhibits SDMA and cell proliferation in HCT116 MTAP-del cells with marked selectivity over HCT116 MTAP-WT cells. This compound selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma, and exhibits a favorable ADME profile.
- Potent and selective PRMT5-MTA complex inhibitor
- Inhibits SDMA and cell proliferation in MTAP-del cells
- Demonstrates dose-dependent inhibition of SDMA in MTAP-del tumors
- Selectively targets MTAP/CDKN2A-deleted tumors, including glioblastoma
- Favorable ADME profile with high bioavailability and moderate to high clearance
Medchemexpress LLC (E/Z)-Zotiraciclib citrate | 1204918-73-9 | C29H32N4O8 | 50 MG
(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. This compound is supplied as a solid, appearing off-white to light yellow, and is intended for research use only.
- Potent CDK2, JAK2, and FLT3 inhibitor
- High purity: 99.83%
- Molecular weight: 564.59
- Store at 4°C, sealed, away from moisture
Crescent Chemical Co Inc TRIS-(2-CARBOXYETHYL)PHOSPHINE
Tris-(2-carboxyethyl)phosphine hydrochloride Water-soluble and odorless reagent for selective and fast reduction of disulfides. Does not react with other functional groups of proteins. Unreactive towards many common alkylating reagents, so reductions have been carried out simultaneously wit
![eMolecules 2902-68-3 | IODOSODILACTONE | AstaTech | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455953.PNG-250.jpg)
eMolecules 2902-68-3 | IODOSODILACTONE | AstaTech | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327
IODOSODILACTONE | AstaTech | 2902-68-3 | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327
Selleck Chemical LLC Clomifene citrate S2561-1g
Clomifene citrate (NSC 35770 Clomiphene citrate) is a selective estrogen receptor modulator used in the treatment of ovulation induction
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl) ester | 462100-06-7 | ≥97.0% | 307.34 | 250 MG
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC. PROTACs (Proteolysis Targeting Chimeras) consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Suitable for PROTAC synthesis
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC (Z)-aconitic acid | 585-84-2 | MFCD00063184 | 99.3% | 174.11 g/mol | C6H6O6 | 5 MG
(Z)-aconitic acid is a small-molecule endogenous metabolite (cis-aconitic acid) reported to act as a glutamate decarboxylase inhibitor with activity that includes reduction of IκB-α phosphorylation and inhibition of inflammatory responses; supplied as a solid for research use.
- Molecular formula C6H6O6 and molecular weight 174.11 g/mol.
- High reported purity (99.28%).
- Reported activity as a glutamate decarboxylase inhibitor and modulator of IκB-α phosphorylation.
- Applicable to research on inflammatory and metabolic pathways.
- Powder stability: -20°C for long-term storage; defined solvent storage conditions available.
Medchemexpress LLC Sparfosic acid trisodium | 70962-66-2 | 98.0% | 321.06 | 100 MG
Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase, an enzyme that catalyzes the second step of de novo pyrimidine biosynthesis. It synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines. This product is for research use only and not intended for sale to patients.
- Potent inhibitor of aspartate transcarbamoyl transferase.
- Synergistically enhances cytotoxicity of 5-FU and IFN against human colon cancer cell lines.
- Causes apoptosis in resistant Br1 cells.
- Leads to progressive accumulation of cells in S phase and activation of an apoptotic pathway.
- Increases lifespan and is curative in mice models of B16 melanoma and Lewis lung carcinoma.
![Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659985.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 1 G
Methylumbelliferyl β-D Glucopyranoside Monohydrate, 1 g is a high-purity reagent used in biochemical analysis to study glucosidase enzyme activity. When cleaved by glucosidases, this substrate releases a fluorescent product, which can be measured in enzyme assays. This property makes it essential in the study of enzyme kinetics and metabolic processes. It is frequently used in laboratory research for microbial assays, diagnostic testing, and in studying enzymatic reactions in various biological systems. The high purity and sensitivity of this reagent ensure reliable and reproducible results in applications that require precise enzyme activity detection.